What is the PCA3 test and where can I find out how to get it?
PCA3 is short for Prostate CAncer gene 3. PCA3 genes in the prostate cells make the cells produce a protein. When prostate cancer cells are present more of this particular protein is produced.
The PCA3 test is a urine test which measures the PCA3 protein commonly expressed in prostate cancer. The prostate gland is massaged to release prostate cells into the urine. This is done in a similar way to a digital rectal examination. A urine sample is then taken to be tested.
Further research is being done to look at how accurate the PCA3 test is and when it is most appropriate to use.
The test appears to be most suitable for men with raised PSA levels following a negative prostate biopsy. It is carried out to provide additional information as to whether a repeat biopsy is needed and does not in itself diagnose cancer. If a man has a positive PCA3 test result, he will still need to undergo a prostate biopsy.
Currently the PCA3 test is not available on the NHS and costs over £300. The following laboratories offer this test privately. You can contact them directly for further information including how to obtain the test. You may also wish to discuss the PCA3 test with your doctor.
For more information on the PCA3 test, read our position statement.
Bostwick Laboratories
Fitzroy Square
London, W1T 5HE
Telephone: 020 7255 9700
The Doctors Laboratory
60 Whitfield Street
London, W1T 4EU
Telephone 020 7307 7373
Medi-Lab
Michigan Avenue
Salford Quays
Manchester M50 2GY
Telephone 0161 877 6336
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To be reviewed: February 2010