Your treatment options will depend on whether your cancer
is contained within the prostate gland (localised), has spread just
outside of the prostate (locally advanced) or had spread
to other parts of the body (advanced).
If the cancer is contained within the prostate gland then there
are treatments available that aim to get rid of the cancer
completely, such as surgery to remove the prostate or radiotherapy.
If the cancer has spread outside of prostate gland then
treatment is usually aimed at controlling the cancer or managing
symptoms.
Your choice of treatment may depend on many factors
including:
- The possible side effects of each treatment
- The advantages and disadvantages of the treatment, including
practical aspects of treatment such as how often you would need to
go to hospital
- Your general views about different treatments, for example some
men prefer to have their prostate gland removed, while others may
not like the idea of surgery
- How your cancer is behaving
- Your general health
You may hear stories in the news about new medicines
(also called drugs) for treating advanced prostate
cancer. New medicines are often not widely
available on the NHS in the UK. Your specialist team may need
to apply
to get new medicines for you if they are not available in your
area.
Select the stage of your cancer below to see which
treatments may be available to you.
Updated February 2010
To be reviewed February 2012
You may hear stories in the news about new medicines
(also called drugs) for treating prostate cancer that has spread
outside of the prostate gland (advanced prostate cancer). New
medicines you may have heard about include cabazitaxel (Jetvana®)
and abiraterone (Zytiga®).
Watchful waiting is a way of monitoring prostate cancer that is
not causing any symptoms or problems. The aim is to monitor the
cancer over the long term because prostate cancer is often slow
growing and may not cause you any symptoms or problems in your
lifetime.
Active surveillance is a way of monitoring prostate cancer which
aims to avoid or delay unnecessary treatment in men with less
aggressive cancer.
Many prostate cancers are detected at an early stage. Prostate
cancer can be slow growing and, for many men, the disease may never
progress or cause any symptoms.
Treatments for prostate cancer can cause side effects which can
affect your quality of life. By monitoring the cancer, you can
avoid or delay these side effects.
Cryotherapy treats prostate cancer by using freezing and thawing
to kill the cancer cells in the prostate gland. It is also
sometimes known as cryosurgery and cryoablation.
Cryotherapy is most commonly an option for men whose prostate
cancer has come back after treatment with radiotherapy or
brachytherapy. It is less often offered as a first treatment for
prostate cancer. However, it may be an option for men who are
unable to have surgery to treat prostate cancer.
Hormone therapy helps control prostate cancer by stopping the
production of testosterone or stopping testosterone reaching the
prostate cancer cells. There are different types of hormone therapy
available, you may have injections, an operation, tablets or
implants. Hormone therapy can cause side effects such as hot
flushes, loss of sex drive and tiredness. It is important that you
are aware of the side effects before you start treatment.
Permanent seed brachytherapy, also known as low dose rate
brachytherapy, involves having tiny radioactive seeds implanted in
your prostate gland. Radiation from the seeds destroys cancer cells
in the prostate. You may have this treatment on its own or together
with external beam radiotherapy and/or hormone therapy. It is just
as good at controlling prostate cancer as other treatments.
High dose rate (HDR) brachytherapy, also known as temporary
brachytherapy, involves inserting a source of high-dose radiation
into the prostate gland for a few minutes at a time to destroy
cancer cells. You may have this treatment on its own or you may
have it together with external beam radiotherapy and/or hormone
therapy.
Bisphosphonates are drugs that can help men with prostate cancer
that has spread to the bones and is no longer responding to hormone
therapy. They do not actually treat the cancer but they can help to
relieve bone pain. They may also help to prevent and slow down the
breakdown of bone.
Men with advanced prostate cancer may have radiotherapy to help
relieve symptoms. This is called palliative radiotherapy.
Palliative radiotherapy does not aim to get rid of your cancer but
it can help to slow down its growth. There are two types of
palliative radiotherapy: external beam radiotherapy (EBRT) and
internal radiotherapy (radioisotopes).
A clinical trial is a type of medical research study that aims
to find new and improved ways of preventing, diagnosing, treating
and controlling illnesses, such as prostate cancer. Clinical
trials involve testing new medicines and procedures on people in a
controlled and carefully planned way. Clinical trials are the best
way to find out whether a new treatment is better than the current
standard treatment.
Radical prostatectomy is an operation to remove the prostate gland
and the cancer contained within it. You may be suitable for this
treatment if your cancer is thought to be contained within the
prostate gland and you are otherwise fit and healthy.
HIFU uses high frequency ultrasound waves to heat and destroy
cancer cells in the prostate. It is a relatively new treatment and
we do not know very much about how effective it is at treating
prostate cancer in the long-term or how it may affect your everyday
life. Because of this, HIFU is only available in a few centres in
the UK, usually as part of a clinical trial.
Chemotherapy uses anti-cancer (cytotoxic) drugs to kill cancer
cells. It is used to help control symptoms and not to cure prostate
cancer. The side effects of chemotherapy are sometimes
difficult to cope with so you need to be reasonably fit before you
begin treatment. You may have chemotherapy alongside other
treatments such as palliative radiotherapy, bisphosphonates,
pain-relieving drugs, and steroids.
External beam radiotherapy uses high energy X-ray beams to treat
prostate cancer. The X-ray beams are directed at the prostate gland
from outside the body. They damage the cancer cells and stop them
growing.
External beam radiotherapy is sometimes given alongside
brachytherapy or high dose rate brachytherapy (internal
radiotherapy). Radiotherapy can also be used after surgery if your
PSA level starts to rise or if not all the cancer was removed with
surgery.
If your prostate cancer is no longer responding to your original
hormone therapy you can have further treatments. You may be able to
have other types of hormone therapy, chemotherapy or a new
treatment as part of a clinical trial.